How's this for a mind-blower:
Schizophrenia, gluten, and low-carbohydrate, ketogenic diets: a case report and review of the literature
Synopsis: 70-year-old schizophrenic experienced complete remission of symptoms after adopting a low-carbohydrate diet. Now, of course, this is just one case study, and needs to be replicated a LOT more times. But it really caught my eye, as from my last post I've been thinking about the mental effects of diet, particularly grains. Schizophrenia is one extreme case of neurological disturbance, but as with all things biological, disease expression is rarely binary. The manifestation of symptoms covers a spectrum when viewed across the population. We just tend to pay the most attention to the extreme cases. Suppose grains were implicated as causal in schizophrenia. It's a good bet they then contribute to other less obvious forms of mental disturbance. Since grains are so widely consumed, this may be actually viewed as the "norm".
Indeed, other neurological conditions are known to benefit from removal of dietary grains, including pediatric epilepsy (discussed in the paper), ADHD, autism, and multiple sclerosis. I've been doing some poking around on wheat germ agglutinin and the brain. Turns out WGA does indeed cross the blood-brain barrier, will bind to insulin receptors in the brain, and probably all kinds of other stuff as well. Google "WGA brain", and you'll find WGA is actually used extensively to map out neuronal pathways, so clearly has potential neurological effects beyond just binding to insulin receptors.
I propose that the sequel to "Fat Head" be "Wheat Head". That covers a lot of ground, from Weston A. Price's observations on cranial development (there definitely seems to be distinct "Wheat Head" phenotypes), to dental disease to the neurological implications, and probably more.
Wouldn't it be fun if the food pyramid were making us fat, sick, deformed, and crazy all at once?